Every FDIC-insured bank branch in DeSoto County, Mississippi as of June 30, 2025. County land area: 476 square miles, 12.6 branches per 100 sq mi.
| Institution | Branches | Deposits |
|---|---|---|
| Cadence Bank | 10 | $1.32B |
| Renasant Bank | 6 | $621.2M |
| Trustmark National Bank | 6 | $287.9M |
| BankPlus | 5 | $313.0M |
| Regions Bank | 4 | $434.5M |
| First Security Bank | 4 | $180.4M |
| Guaranty Bank and Trust Company | 3 | $181.7M |
| First Horizon Bank | 3 | $411.2M |
| The Citizens National Bank of Meridian | 3 | $98.7M |
| Community Bank of Mississippi | 3 | $199.7M |
| Southern Bancorp Bank | 2 | $26.4M |
| FSNB, National Association | 2 | $2.1M |
| Planters Bank & Trust Company | 2 | $76.7M |
| BankFirst Financial Services | 2 | $58.2M |
| Bank3 | 1 | $20.6M |
| Wells Fargo Bank, National Association | 1 | $110.2M |
| FIRST COMMERCIAL BANK | 1 | $62.1M |
| JPMorgan Chase Bank, National Association | 1 | $24.4M |
| Truist Bank | 1 | $113.7M |